Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ HIF-1 Inhibitor
The HIF-1 Inhibitor, also referenced under CAS 934593-90-5, controls the biological activity of HIF-1.
MilliporeSigma™ Calbiochem™ TNF-α Antagonist
The TNF-α Antagonist controls the biological activity of TNF-α.
MilliporeSigma™ Calbiochem™ BRD2 Inhibitor II, BIC1
The BRD2 Inhibitor II, BIC1 controls the biological activity of BRD2.
MilliporeSigma™ Calbiochem™ PKR Inhibitor
The PKR Inhibitor, also referenced under CAS 608512-97-6, controls the biological activity of PKR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ JmjC Histone Demethylase Inhibitor, n-Octyl-IOX1
A cell-permeable, superior inhibitor of Jumonji C domain histone lysine demethylase. About 30 fold more potent than IOX1 (EC50 = 3.8 μM for KDM4A in HeLa cells vs. 100 μM for IOX1).
MilliporeSigma™ Calbiochem™ Iberiotoxin, Buthus tamulus, Recombinant, E. coli
Recombinant Buthus tamulus iberiotoxin expressed in E.
MilliporeSigma™ Calbiochem™ PKCη Pseudosubstrate Inhibitor, Myristoylated
The PKCη Pseudosubstrate Inhibitor, Myristoylated controls the biological activity of PKCη. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Ezh2 Inhibitor II, EI1
A cell-permeable indolocarboxamide compound
MilliporeSigma™ Calbiochem™ LFM-A13
A potent, cell-permeable, reversible, substrate competitive, and specific inhibitor of Bruton's Tyrosine Kinase (BTK; IC50 = 17.2μM for human BTK
MilliporeSigma™ Calbiochem™ Cathepsin K Inhibitor III
The Cathepsin K Inhibitor III controls the biological activity of Cathepsin K. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ TGF-β RI Kinase Inhibitor IX
A cell-permeable pyridinyloxypyridine compound that acts as a potent and highly selective inhibitor against TGFβ RI/ALK5 (IC50 = 72 nM, [ATP] = 1 mM) by targeting both the ATP-binding site and the selectivity pocket, while exhibiting much reduced or little activity against a panel of 75 other kinases (IC50 <1μM).
MilliporeSigma™ Calbiochem™ SB-269970 Hydrochloride
A selective 5-HT7 receptor antagon
MilliporeSigma™ Calbiochem™ α-(Methylamino)isobutyric Acid
A glutamine transport inhibitor selective for Na+-dependent amino acid transport system A.
MilliporeSigma™ Calbiochem™ HNMPA-(AM)3
A cell-permeable analog of HNMPA that yields the parent compound upon cleavage by cytosolic esterases.
MilliporeSigma™ Calbiochem™ MMP-2/MMP-9 Substrate I, Fluorogenic
A fluorogenic substrate for both the 72 kDa human fibroblast gelatinase (HFG; MMP-2) and the 92 kDa human neutrophil gelatinase (HNG; MMP-9).